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Hyphenated mass spectrometry strategies as tools for unveiling peptide toxins with potential therapeutic application

Guest editors: Daniel Pimenta and Philippe Bulet
Hyphenated mass spectrometry strategies as tools for unveiling peptide toxins with potential therapeutic application


Journal of Venomous Animals and Toxins including Tropical Diseases is now accepting submissions to be considered for publication in a thematic series on hyphenated mass spectrometry strategies as tools for unveiling peptide toxins with potential therapeutic application.

Edited by Daniel Pimenta (Butantan Institute, Brazil) and Philippe Bulet (University Grenoble Alpes, France) as guest editors, the collection will accept research and review manuscript submissions and will also include commissioned topical reviews, written by leaders in the field.

Hyphenated mass spectrometry (MS) strategies have been successfully employed as tools for unveiling peptide toxins and other bioactive peptides, such as proteins from venoms and secretions. The association of genome mining, complementary “omics” and/or bar-coding of complex matrices with structural characterization by MS and pharmacological studies on the structure-activity relationship of such novel molecules provides armamentarium for new therapeutics targets and candidates.

Under this broad thematic umbrella, the series will cover research topics on peptides with functional properties such as antimicrobial, toxic, lytic, vasoactive, anti-proliferative, antiviral, anti-tumoral, immunomodulators and enzyme inhibitors.

The deadline for submissions is May 10th 2017.

Manuscripts should be formatted according to our submission guidelines and submitted via the online submission system. In the submission system please make sure the correct collection title is chosen from the additional information tab. Please also indicate clearly in the covering letter that the manuscript is to be considered for the Hyphenated Mass Spectrometry Strategies as Tools for Unveiling Peptide Toxins with Potential Therapeutic Application series.

If you would like to enquiry about the suitability of a manuscript for consideration, please email a pre-submission enquiry to editorial@jvat.org.br.


Research  |  Peptidomic investigation of Neoponera villosa venom by high-resolution mass spectrometry: seasonal and nesting habitat variations
Camila Takeno Cologna, Renata Santos Rodrigues, Jean Santos, Edwin de Pauw, Eliane Candiani Arantes and Loïc Quinton
» Full Text       » PDF

Research  |  Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening
Tarek Mohamed Abd El-Aziz, Sawsan Al Khoury, Lucie Jaquillard, Mathilde Triquigneaux, Guillaume Martinez, Sandrine Bourgoin-Voillard, Michel Sève, Christophe Arnoult, Rémy Beroud and Michel De Waard
» Full Text       » PDF

Research  |  Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions
Laudicéia Alves de Oliveira, Rui Seabra Ferreira Jr, Benedito Barraviera, Francilene Capel Tavares de Carvalho, Luciana Curtolo de Barros, Lucilene Delazari dos Santos and Daniel Carvalho Pimenta
» Full Text       » PDF

Review  |  It is time for top-down venomics
Rafael D. Melani, Fabio C. S. Nogueira and Gilberto B. Domont
» Full Text       » PDF

Research  |  Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the Echinometra lucunter spines extracts
Juliana Mozer Sciani, Bianca Zychar, Luis Roberto Gonçalves, Renata Giorgi, Thiago Nogueira and Daniel Carvalho Pimenta
» Full Text       » PDF

Research  |  Peptidomic analysis of the venom of the solitary bee Xylocopa appendiculata circumvolans
Kohei Kazuma, Kenji Ando, Ken-ichi Nihei, Xiaoyu Wang, Marisa Rangel, Marcia Regina Franzolin, Kanami Mori-Yasumoto, Setsuko Sekita, Makoto Kadowaki, Motoyoshi Satake and Katsuhiro Konno
» Full Text       » PDF

Research  |  Isolation and biochemical characterization of bradykinin-potentiating peptides from Bitis gabonica rhinoceros
Tamara M. Fucase, Juliana M. Sciani, Ingrid Cavalcante, Vincent L. Viala, Bruno B. Chagas, Daniel C. Pimenta and Patrick J. Spencer
» Full Text       » PDF

Research  |  Ergosterol isolated from the basidiomycete Pleurotus salmoneostramineus affects Trypanosoma cruzi plasma membrane and mitochondria
Tatiana Rodrigues Alexandre, Marta Lopes Lima, Mariana Kolos Galuppo, Juliana Tonini Mesquita, Matilia Ana do Nascimento, Augusto Leonardo dos Santos, Patricia Sartorelli, Daniel Carvalho Pimenta and Andre Gustavo Tempone
» Full Text       » PDF

Research  |  Isolation of biologically active peptides from the venom of Japanese carpenter bee, Xylocopa appendiculata
Hiroko Kawakami, Shin G. Goto, Kazuya Murata, Hideaki Matsuda, Yasushi Shigeri, Tomohiro Imura, Hidetoshi Inagaki and Tetsuro Shinada
» Full Text       » PDF

Review  |  Protein-species quantitative venomics: looking through a crystal ball
Juan J. Calvete, Daniel Petras, Francisco Calderón-Celis, Bruno Lomonte, Jorge Ruiz Encinar and Alfredo Sanz-Medel
» Full Text       » PDF

Review  |  Strategies in ‘snake venomics’ aiming at an integrative view of compositional, functional, and immunological characteristics of venoms
Bruno Lomonte and Juan J. Calvete
» Full Text       » PDF